| dw | vw | 2e jaargang nummer 51, zaterdag 18 december 2021 (nummer 102) | a.w. | h.p | score |
| 1 | 1 | EASY ON ME — Adele | 8 | 7×1 | 389 |
| 2 | 2 | AMSTERDAM — Flemming | 8 | 2 | 338 |
| 3 | 3 | SHIVERS — Ed Sheeran | 13 | 1×1 | 596 |
| 4 | 5 | DO IT TO IT — Acraze feat. Cherish | 6 | 2 | 252 |
| 5 | 4 | COLD HEART — Elton John & Dua Lipa (F) | 17 | 3×1 | 753 |
| 6 | 8 | DAT HEB JIJ GEDAAN — Meau | 4 | 6 | 126 |
| 7 | 27 | ABCDEFU — Gayle | 2 | 7 | 68 |
| 8 | 6 | PEPAS — Farruko | 15 | 2 | 650 |
| 9 | 28 | WATERVAL — K3 (F) | 2 | 9 | 65 |
| 10 | — | MERRY CHRISTMAS — Ed Sheeran & Elton John (F) | 1 | 10 | 41 |
| 11 | 7 | HEAT WAVES — Glass Animals | 13 | 5 | 545 |
| 12 | 9 | WHERE ARE YOU NOW — Lost Frequencies / Calum Scott | 16 | 6 | 630 |
| 13 | 11 | STAY — The Kid Laroi & Justin Bieber | 22 | 2×1 | 1013 |
| 14 | 13 | OVERPASS GRAFFITI — Ed Sheeran (F) | 6 | 12 | 212 |
| 15 | 21 | STREKEN VAN EEN DUIVEL — Bilal Wahib feat. Frenna | 3 | 15 | 79 |
| 16 | 10 | MY UNIVERSE — Coldplay x BTS | 11 | 8 | 412 |
| 17 | 14 | THUNDER — Gabry Ponte x Lum!x x Prezioso | 9 | 14 | 248 |
| 18 | 12 | NOG EENTJE DAN — Frans Duijts (F) | 4 | 12 | 133 |
| 19 | 23 | BRUXELLES JE T’AIME — Angele | 7 | 19 | 187 |
| 20 | 42 | VLUCHTSTROOK — Kris Kross Amsterdam, Antoon & Sigourney | 2 | 20 | 40 |
| 21 | 17 | CHRISTMAS ON MY DOORSTEP — Og3ne (F) | 3 | 17 | 84 |
| 22 | 16 | THAT’S WHAT I WANT — Lil Nas X | 11 | 11 | 376 |
| 23 | 19 | BON GEPAKT — Donnie feat. Rene Froger | 14 | 6 | 506 |
| 24 | 18 | LOVE TONIGHT — Shouse | 21 | 1×1 | 878 |
| 25 | 20 | HARD TO SAY GOODBYE — Ronde | 11 | 18 | 259 |
| 26 | 22 | ZE MEENT HET — Metejoor | 6 | 22 | 130 |
| 27 | 26 | MOTH TO A FLAME — Swedish House Mafia & The Weeknd | 7 | 18 | 186 |
| 28 | 24 | SANTE — Stromae | 8 | 15 | 222 |
| 29 | 25 | LITTLE THINGS — Abba (F) | 5 | 18 | 135 |
| 30 | 33 | IN DE NACHT — Yade Lauren | 7 | 28 | 115 |
| 31 | 15 | DROMEN IN KLEUR — Suzan & Freek | 7 | 11 | 211 |
| 32 | 31 | GHOST — Justin Bieber | 4 | 31 | 56 |
| 33 | 30 | LOVE NWANTITI (AH AH AH) — CKay feat. Joeboy & Kuami Eugene | 13 | 7 | 404 |
| 34 | 44 | THE MOTTO – Tiesto & Ava Max | 2 | 34 | 24 |
| 35 | 29 | BAD HABITS — Ed Sheeran | 24 | 6×1 | 1025 |
| 36 | 35 | DUIZEND STERREN — Regi & Pauline | 11 | 19 | 247 |
| 37 | 32 | VOOR JE VAN ME HOUDT — Jaap Reesema (F) | 8 | 16 | 193 |
| 38 | 37 | JUST A NOTION — Abba | 4 | 37 | 39 |
| 39 | 46 | MEISJES VAN HONING — Pommelien Thijs | 2 | 39 | 17 |
| 40 | 36 | HOLD ON — Armin van Buuren and Davina Michelle | 7 | 31 | 77 |
| 41 | 39 | ONDERWEG — Bazart feat. S10 | 8 | 31 | 105 |
| 42 | 38 | HURRICANE — Ofenbach & Ella Henderson (F) | 12 | 22 | 252 |
| 43 | re | ALL I WANT FOR XMAS IS YOU – Mariah Carey | 7 | 10 | 143 |
| 44 | 40 | DANCING AT THE DOOR OF HEAVEN — Son Mieux (F) | 7 | 21 | 130 |
| 45 | 41 | FREEDOM — Grace [Be] | 9 | 34 | 104 |
| 46 | re | LAST CHRISTMAS – Wham | 7 | 15 | 123 |
| 47 | 34 | REMEMBER — Becky Hill & David Guetta (F) | 24 | 9 | 805 |
| 48 | — | NEEM ER EEN VAN MIJ — Mart Hoogkamer | 1 | 48 | 3 |
| 49 | 49 | STERKER — Niels Destadsbarder | 6 | 48 | 11 |
| 50 | re | ZOLANG JE BIJ ME BENT (F) — Jan Smit | 13 | 15 | 296 |
| Kijk voor de uitzendende stations op www.flitsende50.nl/stations/ | |||||
| Uitzending of overname alleen naar toestemming van Flitsende 50, Postbus 3323, ‘s-Hertogenbosch |