| dw | vw | 2e jaargang nummer 4, zaterdag 23 januari 2021 | a.w. | h.p | score |
| 1 | 1 | NU WIJ NIET MEER PRATEN — Jaap Reesema & Pommelien Thijs | 8 | 4×1 | 344 |
| 2 | 2 | THE BUSINESS — Tiësto | 14 | 1×1 | 574 |
| 3 | 3 | HEAD & HEART — Joel Corry & Mnek | 24 | 2 | 1080 |
| 4 | 4 | YOU BROKE ME FIRST — Tate Mcrae | 15 | 4 | 554 |
| 5 | 5 | HEAD SHOULDERS KNEES & TOES — Ofenbach & Quarterhead (feat. Norma Jean Martine) | 10 | 3 | 389 |
| 6 | 9 | PARADISE — Meduza & Dermot Kennedy | 5 | 6 | 145 |
| 7 | 7 | DOOR DE WIND — Miss Montreal | 14 | 7×1 | 627 |
| 8 | 6 | MOOD — 24kGoldn feat. Iann Dior | 19 | 3 | 818 |
| 9 | 23 | WITHOUT YOU — The Kid Laroi | 3 | 9 | 92 |
| 10 | 26 | ANYONE — Justin Bieber | 2 | 10 | 66 |
| 11 | 19 | AFTERGLOW — Ed Sheeran | 3 | 11 | 89 |
| 12 | 8 | LONELY — Justin Bieber & Benny Blanco | 12 | 5 | 486 |
| 13 | 15 | LOVE NOT WAR – THE TAMPA — Jason Derulo x Nuka | 4 | 13 | 101 |
| 14 | 18 | WHO’S LAUGHING NOW? — Ava Max | 4 | 14 | 122 |
| 15 | 12 | PRISONER — Miley Cyrus feat. Dua Lipa | 6 | 12 | 186 |
| 16 | 10 | LET’S LOVE — David Guetta & Sia | 16 | 10 | 502 |
| 17 | 13 | TAKE YOU DANCING — Jason Derulo | 16 | 11 | 529 |
| 18 | 11 | POSITIONS — Ariana Grande (F) | 11 | 8 | 404 |
| 19 | 35 | ALL WE GOT — Robin Schulz feat. Kiddo | 2 | 19 | 48 |
| 20 | 14 | JERUSALEMA — Master KG ft. Nomcebo | 21 | 2 | 825 |
| 21 | 20 | DON’T LEAVE ME NOW — Lost Frequencies feat. Mathieu Koss (F) | 15 | 14 | 354 |
| 22 | 16 | SOMEONE TO YOU — Banners | 19 | 9 | 636 |
| 23 | 22 | IN DE SCHUUR — Snelle & Ronnie Flex | 12 | 12 | 370 |
| 24 | 24 | FEVER — Dua Lipa feat. Angele | 4 | 23 | 102 |
| 25 | 21 | MONSTER — Shawn Mendes & Justin Bieber | 7 | 11 | 199 |
| 26 | 17 | BLINDING LIGHTS – The Weekend | 40 | 2×1 | 1652 |
| 27 | — | DRIVERS LICENSE — Olivia Rodrigo | 1 | 27 | 24 |
| 28 | 25 | THEREFORE I AM — Billie Eilish | 8 | 12 | 202 |
| 29 | 30 | DYNAMITE — Bts | 17 | 13 | 414 |
| 30 | 42 | GOOSEBUMPS — Hvme | 2 | 30 | 30 |
| 31 | 29 | VECHTER — Regi & Camille | 4 | 29 | 78 |
| 32 | 28 | WONDER — Shawn Mendes (F) | 14 | 17 | 350 |
| 33 | 47 | ALWAYS — Just Bart | 2 | 33 | 22 |
| 34 | 37 | HAWAI – REMIX — Maluma & the Weeknd | 5 | 34 | 51 |
| 35 | 27 | LEMONADE — Internet Money & Gunna feat. Don Toliver & Nav | 15 | 8 | 468 |
| 36 | 38 | DENK MAAR NIET AAN MORGEN — Bazart | 4 | 36 | 46 |
| 37 | 34 | MIDNIGHT SKY — Miley Cyrus | 21 | 11 | 563 |
| 38 | 33 | MAS MAS MAS — Rolf Sanchez | 22 | 7×1 | 788 |
| 39 | 32 | DE OVERKANT — Suzan & Freek & Snelle | 20 | 1×1 | 822 |
| 40 | 31 | HOLY — Justin Bieber & Chance The Rapper | 16 | 6 | 597 |
| 41 | 43 | FOREVER YOURS — Nona | 2 | 41 | 18 |
| 42 | — | MANSORY — Lijpe feat. Frenna | 1 | 42 | 9 |
| 43 | 36 | ZIJ ZAL ER ALTIJD ZIJN — Tino Martin | 17 | 22 | 363 |
| 44 | 39 | STRANGERS — Laura Tesoro & Loic Nottet feat. Alex Germys | 3 | 39 | 22 |
| 45 | 40 | ROLLER COASTER — Danny Vera | 11 | 14 | 237 |
| 46 | 41 | LEVITATING — Dua Lipa feat. Dababy (F) | 13 | 28 | 196 |
| 47 | 46 | HOLIDAY — Lil Nas X | 2 | 46 | 9 |
| 48 | — | GET OUT MY HEAD — Shane Codd | 1 | 48 | 3 |
| 49 | — | LET ME HOLD YOU — Netsky & Hybrid Minds | 1 | 49 | 2 |
| 50 | 48 | WHOOPTY — CJ | 2 | 48 | 4 |
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